Vitamin D Levels in Crohn's Disease

Condition: Crohn's Disease

Eligibility

Key Inclusion Criteria

  • At least 18 years old
  • Diagnosis of Crohn’s disease
  • In clinical remission

Key Exclusion Criteria

  • Clinical disease activity
  • Current pregnancy or attempting to conceive
  • Hypercalcemia (calcium level in blood that is above normal)

Full Study Name

A Double-Blind, Randomized, Placebo-Controlled Trial Evaluating Effective Maintenance Strategies for Optimization of Vitamin D Levels in Patients with Crohn's Disease in Remission (IRB no. 50335)

Summary

This study focuses on patients who have well-controlled Crohn’s disease and low levels of Vitamin D. The purpose of the study is to determine the best strategy to maintain adequate Vitamin D levels in patients with Crohn’s disease who are in clinical remission. Although vitamin supplementation (consuming vitamins in addition to the nutrients in food eaten) is not approved by the Food and Drug Administration as treatment, it is routinely prescribed by physicians for support of bone health and nutrition. Studies have also found that low vitamin D levels are associated with poorer quality of life. Researchers will compare the effects of Vitamin D3 against the effects of a placebo (inactive substance); participants will be randomly assigned to a study group.

Principal Investigator

Gil Melmed, MD

Contact
Elizabeth Khanishian
Phone: 310-423-2041
Email: elizabeth.khanishian@cshs.org